APOBEC3B, apolipoprotein B mRNA editing enzyme catalytic subunit 3B

APOBEC3B, apolipoprotein B mRNA editing enzyme catalytic subunit 3B

• This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

• Gene Synonyms (DNA dC->dU-editing enzyme APOBEC-3B, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B, cytidine deaminase, phorbolin 2, phorbolin 3, phorbolin-1-related protein, phorbolin-2/3, probable DNA dC->dU-editing enzyme APOBEC-3B, A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2,)
• NCBI Gene ID: 9582
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UH17
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

apolipoprotein B mRNA editing enzyme catalytic subunit 3B interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  BCL2 associated transcription factor 1
  dynactin 3
  fused in sarcoma
  matrin 3
  MSL complex subunit 2
  serine and arginine-rich splicing factor 1
  Shc SH2-domain binding protein 1
  small nuclear ribonucleoprotein 70 (U1)
  TATA-box binding protein associated factor 15
  WW domain containing E3 ubiquitin protein ligase 2

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