GPRASP1, G protein-coupled receptor associated sorting protein 1

GPRASP1, G protein-coupled receptor associated sorting protein 1

• This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]

• Gene Synonyms (G-protein coupled receptor-associated sorting protein 1, GASP, GASP-1, GASP1,)
• NCBI Gene ID: 9737
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JY77
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein-coupled receptor associated sorting protein 1 interacts with:

• chromosome 8 open reading frame 33
  G protein-coupled receptor associated sorting protein 2
  glycine-N-acyltransferase
  HGH1 homolog
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
  MAP7 domain containing 1
  metal response element binding transcription factor 2
  PDZ binding kinase
  regulatory associated protein of MTOR complex 1
  SNAP associated protein
  stathmin 2
  trafficking from ER to golgi regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.