PREB, prolactin regulatory element binding

PREB, prolactin regulatory element binding

• This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]

• Gene Synonyms (prolactin regulatory element-binding protein, mammalian guanine nucleotide exchange factor mSec12, SEC12,)
• NCBI Gene ID: 10113
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HCU5
  UNIPROT ID#>>Q05DB2
  UNIPROT ID#>>B5MC98
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prolactin regulatory element binding interacts with:

• acyl-CoA thioesterase 9
  anoctamin 6
  clusterin associated protein 1
  coronin 1C
  cytochrome b5 reductase 1
  egl-9 family hypoxia inducible factor 3
  EvC ciliary complex subunit 2
  inducible T cell costimulator ligand
  limb development membrane protein 1 like
  NHL repeat containing 2
  occludin
  OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  prolactin regulatory element binding
  rhomboid 5 homolog 2
  rhomboid domain containing 1
  ring finger protein 31
  sodium channel and clathrin linker 1
  synoviolin 1
  tectonic family member 2
  tectonic family member 3
  transmembrane protein 17
  transmembrane protein 216
  transmembrane protein 67
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.