SYVN1, synoviolin 1

SYVN1, synoviolin 1

• This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]

• Gene Synonyms (E3 ubiquitin-protein ligase synoviolin, HMG-coA reductase degradation 1 homolog, RING-type E3 ubiquitin transferase synoviolin, synovial apoptosis inhibitor 1, synoviolin, DER3, HRD1,)
• NCBI Gene ID: 84447
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86TM6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synoviolin 1 interacts with:

• 3-hydroxyacyl-CoA dehydratase 2
  glycerol-3-phosphate acyltransferase 4
  lipase maturation factor 2
  oxysterol binding protein like 8
  PDZ domain containing 8
  peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  PPARG coactivator 1 beta
  RAB, member of RAS oncogene family like 3
  small VCP interacting protein
  solute carrier family 24 member 5
  synapse associated protein 1
  synoviolin 1
  torsin 1A interacting protein 2
  transmembrane protein 129, E3 ubiquitin ligase
  UBA domain containing 2
  ubiquitin conjugating enzyme E2 U
  WD repeat domain 20

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.