RNF5, ring finger protein 5

RNF5, ring finger protein 5

• The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. [provided by RefSeq, Jul 2008]

• Gene Synonyms (E3 ubiquitin-protein ligase RNF5, RING-type E3 ubiquitin transferase RNF5, protein G16, ram1 homolog, ring finger protein 5, E3 ubiquitin protein ligase, RING5, RMA1,)
• NCBI Gene ID: 6048
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99942
  UNIPROT ID#>>A0A024RCQ4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ring finger protein 5 interacts with:

• abhydrolase domain containing 16A, phospholipase
  ADP ribosylation factor like GTPase 6 interacting protein 1
  atlastin GTPase 3
  B cell receptor associated protein 31
  BAG cochaperone 6
  bone morphogenetic protein receptor, type 1A
  cytochrome b561 family member A3
  derlin 1
  diacylglycerol O-acyltransferase 2 like 6
  DnaJ heat shock protein family (Hsp40) member C7
  egl-9 family hypoxia inducible factor 3
  ER lipid raft associated 2
  family with sequence similarity 241 member B
  formin homology 2 domain containing 1
  golgi to ER traffic protein 4
  insulin induced gene 2
  JNK1/MAPK8 associated membrane protein
  leptin receptor overlapping transcript like 1
  limb development membrane protein 1 like
  mitochondrial antiviral signaling protein
  multiple PDZ domain crumbs cell polarity complex component
  ORMDL sphingolipid biosynthesis regulator 3
  phospholipid phosphatase 6
  PRA1 domain family member 2
  prostaglandin D2 receptor 2
  Rab acceptor 1
  RAB5C, member RAS oncogene family
  rhomboid domain containing 1
  ring finger protein 185
  ring finger protein 5
  RUS family member 1
  S100 calcium binding protein A8
  SEC22 homolog A, vesicle trafficking protein
  selenoprotein S
  solute carrier family 1 member 1
  solute carrier family 38 member 7
  stearoyl-CoA desaturase
  stimulator of interferon response cGAMP interactor 1
  survival motor neuron 1
  TNF alpha induced protein 3
  transforming growth factor beta receptor 1
  translocase of outer mitochondrial membrane 40
  transmembrane protein 120B
  transmembrane protein 242
  tubulin alpha 1c
  ubiquitin C
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 D2
  ubiquitin conjugating enzyme E2 D3
  ubiquitin conjugating enzyme E2 D4 (putative)
  ubiquitin conjugating enzyme E2 E1
  ubiquitin conjugating enzyme E2 E2
  ubiquitin conjugating enzyme E2 E3
  ubiquitin conjugating enzyme E2 G2
  ubiquitin conjugating enzyme E2 J1
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 U
  ubiquitin conjugating enzyme E2 V1
  ubiquitin conjugating enzyme E2 W
  ubiquitin conjugating enzyme E2 Z
  ubiquitin domain containing 1
  X-ray repair cross complementing 3
  Yip1 domain family member 1
  Yip1 domain family member 2
  Yip1 domain family member 4
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.