TYRO3, TYRO3 protein tyrosine kinase

TYRO3, TYRO3 protein tyrosine kinase

• The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]

• Gene Synonyms (tyrosine-protein kinase receptor TYRO3, tyrosine-protein kinase DTK, tyrosine-protein kinase RSE, tyrosine-protein kinase SKY, tyrosine-protein kinase TIF, tyrosine-protein kinase byk, BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif,)
• NCBI Gene ID: 7301
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H0YNK6
  UNIPROT ID#>>Q06418
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TYRO3 protein tyrosine kinase interacts with:

• alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  COP9 signalosome subunit 5
  CTD small phosphatase 1
  CTD small phosphatase 2
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  inositol-pentakisphosphate 2-kinase
  kallikrein related peptidase 4
  keratin 40
  keratin associated protein 10-3
  keratin associated protein 10-7
  keratin associated protein 10-8
  keratin associated protein 10-9
  keratin associated protein 4-2
  keratin associated protein 9-2
  ligand of numb-protein X 1
  TNFAIP3 interacting protein 1
  transmembrane protein 30B
  tubulin tyrosine ligase-like family, member 12
  von Willebrand factor C domain containing 2 like
  YES proto-oncogene 1, Src family tyrosine kinase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.