PRDX6, peroxiredoxin 6

PRDX6, peroxiredoxin 6

• The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

• Gene Synonyms (peroxiredoxin-6, 1-Cys PRX, 1-Cys peroxiredoxin, 24 kDa protein, acidic calcium-independent phospholipase A2, antioxidant protein 2, epididymis secretory sperm binding protein Li 128m, glutathione-dependent peroxiredoxin, liver 2D page spot 40, non-selenium glutathione peroxidase, red blood cells page spot 12, 1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29,)
• NCBI Gene ID: 9588
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HWC7
  UNIPROT ID#>>P30041
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

peroxiredoxin 6 interacts with:

• 6-phosphogluconolactonase
  AAR2 splicing factor
  abhydrolase domain containing 11
  activator of HSP90 ATPase activity 1
  ankyrin repeat and SOCS box containing 12
  ankyrin repeat and SOCS box containing 3
  anterior gradient 2, protein disulphide isomerase family member
  CD2 associated protein
  chloride intracellular channel 4
  chromosome 11 open reading frame 54
  chromosome 11 open reading frame 58
  cullin 7
  cytochrome c oxidase assembly factor 7 (putative)
  dual specificity phosphatase 13
  dynamin 1 like
  enolase-phosphatase 1
  ferredoxin 2
  G3BP stress granule assembly factor 1
  glutaredoxin 5
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  histidine triad nucleotide binding protein 2
  histone deacetylase 5
  ISG15 ubiquitin like modifier
  lactamase beta 2
  leucine aminopeptidase 3
  lysophospholipase 1
  mitogen-activated protein kinase 13
  myotrophin
  neudesin neurotrophic factor
  NHL repeat containing 2
  nitrilase family member 2
  Parkinsonism associated deglycase
  PAX interacting protein 1
  peptidase, mitochondrial processing subunit alpha
  peptidyl-tRNA hydrolase domain containing 1
  peroxiredoxin 5
  peroxiredoxin 6
  phosphoethanolamine/phosphocholine phosphatase 1
  PIH1 domain containing 1
  pitrilysin metallopeptidase 1
  plasmanylethanolamine desaturase 1
  pleckstrin homology domain containing A4
  pre-mRNA processing factor 8
  prostaglandin reductase 1
  protein phosphatase targeting COQ7
  PTEN induced kinase 1
  pyruvate dehyrogenase phosphatase catalytic subunit 1
  saitohin
  serine carboxypeptidase 1
  small ubiquitin like modifier 4
  SSU72 homolog, RNA polymerase II CTD phosphatase
  surfactant protein A1
  TERF2 interacting protein
  translocase of inner mitochondrial membrane 9
  transmembrane p24 trafficking protein 10
  tripartite motif containing 14
  ubiquitin C-terminal hydrolase L5
  vir like m6A methyltransferase associated
  WD repeat domain 1
  Yes1 associated transcriptional regulator
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.