- Gene Overview
- Interaction Network
- Sequence Verification
PARP3, poly(ADP-ribose) polymerase family member 3
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The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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Gene Synonyms (protein mono-ADP-ribosyltransferase PARP3, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3, ADP-ribosyltransferase diphtheria toxin-like 3, ADPRT-3, DNA ADP-ribosyltransferase PARP3, NAD(+) ADP-ribosyltransferase 3, NAD+ ADP-ribosyltransferase 3, poly [ADP-ribose] polymerase 3, poly(ADP-ribose) synthetase-3, poly[ADP-ribose] synthase 3, poly[ADP-ribose] synthetase 3, ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3,)
- NCBI Gene ID:
10039
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>A0A024R2X5
UNIPROT ID#>>Q9Y6F1
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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poly(ADP-ribose) polymerase family member 3 interacts with:
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