CELF1, CUGBP Elav-like family member 1

CELF1, CUGBP Elav-like family member 1

• Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50, CUGBP Elav-like family member 1, 50 kDa nuclear polyadenylated RNA-binding protein, CUG RNA-binding protein, CUG triplet repeat RNA-binding protein 1, CUG-BP- and ETR-3-like factor 1, EDEN-BP homolog, RNA-binding protein BRUNOL-2, bruno-like 2, bruno-like protein 2, deadenylation factor CUG-BP, embryo deadenylation element binding protein, embryo deadenylation element-binding protein homolog, nuclear polyadenylated RNA-binding protein, 50-kD,)
• NCBI Gene ID: 10658
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92879
  UNIPROT ID#>>G5EA30
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CUGBP Elav-like family member 1 interacts with:

• ceramide kinase
  coiled-coil domain containing 88A
  CUGBP Elav-like family member 1
  myosin, heavy polypeptide 9, non-muscle
  RALY heterogeneous nuclear ribonucleoprotein
  ring finger and CCCH-type domains 1
  TAR DNA binding protein
  WD repeat domain 76

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