GBP5, guanylate binding protein 5

GBP5, guanylate binding protein 5

• This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]

• Gene Synonyms (GBP-5, guanylate-binding protein 5, GBP-TA antigen, GTP-binding protein 5, guanine nucleotide-binding protein 5,)
• NCBI Gene ID: 115362
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96PP8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

guanylate binding protein 5 interacts with:

• acyl-CoA synthetase medium chain family member 1
  guanylate binding protein 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.