- Gene Overview
- Interaction Network
- Sequence Verification
TAF8, TATA-box binding protein associated factor 8
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This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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Gene Synonyms (II, TAF, TAF(II)43, TAFII-43, TAFII43, TBN, transcription initiation factor TFIID subunit 8, TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa, TBP-associated factor 43 kDa, TBP-associated factor 8, TBP-associated factor TAFII43, TBP-associated factor, RNA polymerase II, 43 kD, hTAFII43, protein taube nuss, taube nuss homolog, transcription initiation factor TFIID 43 kDa subunit,)
- NCBI Gene ID:
129685
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q7Z7C8
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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TATA-box binding protein associated factor 8 interacts with:
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