Musk, muscle, skeletal, receptor tyrosine kinase

Musk, muscle, skeletal, receptor tyrosine kinase

• This gene encodes a member of the protein tyrosine kinase family. The encoded protein is a type 1 receptor-like protein located in muscle membrane that is activated by the heparan sulfate proteoglycan agrin released by nerve cells. The encoded protein activates signaling cascades responsible for multiple aspects of motor neuron and muscle development, including organization of the postsynaptic membrane, synaptic gene transcription, patterning of skeletal muscle, anchoring of acetylcholinesterase, and guidance of motor axons. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• (No alternate names found)
• NCBI Gene ID: 18198
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q1XD56
  UNIPROT ID#>>Q32SD3
  UNIPROT ID#>>Q61006
  UNIPROT ID#>>E9PVV8
  UNIPROT ID#>>Q497X0
  UNIPROT ID#>>Q32S49
  UNIPROT ID#>>Q32S50
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

muscle, skeletal, receptor tyrosine kinase interacts with:

• docking protein 7
  muscle, skeletal, receptor tyrosine kinase
  p21 (RAC1) activated kinase 1
  ring finger protein 31

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