PRIMPOL, primase and DNA directed polymerase

PRIMPOL, primase and DNA directed polymerase

• This gene encodes a DNA primase-polymerase that belongs to a superfamily of archaeao-eukaryotic primases. Members of this family have primase activity, catalyzing the synthesis of short RNA primers that serve as starting points for DNA synthesis, as well as DNA polymerase activity. The encoded protein facilitates DNA damage tolerance by mediating uninterrupted fork progression after UV irradiation and reinitiating DNA synthesis. An allelic variant in this gene is associated with myopia 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• Gene Synonyms (DNA-directed primase/polymerase protein, coiled-coil domain-containing protein 111, hPrimpol1, CCDC111, MYP22, Primpol1,)
• NCBI Gene ID: 201973
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96LW4
  UNIPROT ID#>>D3DP56
  UNIPROT ID#>>A0A0A0MTC0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

primase and DNA directed polymerase interacts with:

• primase and DNA directed polymerase

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