PLCB1, phospholipase C beta 1

PLCB1, phospholipase C beta 1

• The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (EIEE12, PI-PLC, PLC-154, PLC-I, PLC-beta-1, PLC154, PLCB1A, PLCB1B, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, phosphoinositidase C, phosphoinositide phospholipase C, phospholipase C, beta 1 (phosphoinositide-specific), phospholipase C-I, triphosphoinositide phosphodiesterase,)
• NCBI Gene ID: 23236
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NQ66
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase C beta 1 interacts with:

• centrosomal protein 76
  differentially expressed in FDCP 8 homolog
  par-3 family cell polarity regulator
  par-6 family cell polarity regulator alpha
  PCF11 cleavage and polyadenylation factor subunit
  phospholipase C beta 1
  transient receptor potential cation channel subfamily M member 7
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.