PHPT1, phosphohistidine phosphatase 1

PHPT1, phosphohistidine phosphatase 1

• This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

• Gene Synonyms (14 kDa phosphohistidine phosphatase, epididymis secretory sperm binding protein Li 132P, protein histidine phosphatase, protein janus-A homolog, sex-regulated protein janus-a, CGI-202, HEL-S-132P, HSPC141, PHP, PHP14,)
• NCBI Gene ID: 29085
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NRX4
  UNIPROT ID#>>V9HWC4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphohistidine phosphatase 1 interacts with:

• aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  ataxin 1 like
  chromosome 5 open reading frame 51
  DNA methyltransferase 3 like
  GDP-D-glucose phosphorylase 1
  leucine rich repeat containing 1
  leucine rich repeat kinase 2
  nudix hydrolase 9
  protein phosphatase 1 regulatory subunit 16A
  ribokinase
  trafficking protein particle complex 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.