CARD10, caspase recruitment domain family member 10

CARD10, caspase recruitment domain family member 10

• The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (caspase recruitment domain-containing protein 10, Bcl10 binding protein and activator of NFKB, CARD-containing MAGUK 3 protein, CARD-containing MAGUK protein 3, carma 3, BIMP1, CARMA3,)
• NCBI Gene ID: 29775
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BWT7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

caspase recruitment domain family member 10 interacts with:

• BCL6B transcription repressor
  caspase recruitment domain family member 10
  caspase recruitment domain family member 9
  cation channel sperm associated 1
  centrosomal protein 95
  chromobox 8
  chromosome 4 open reading frame 45
  chromosome 8 open reading frame 48
  coiled-coil domain containing 116
  coiled-coil domain containing 187
  CWF19 like cell cycle control factor 2
  C-X-C motif chemokine ligand 16
  cysteine rich tail 1
  DExH-box helicase 57
  dual specificity phosphatase 26
  family with sequence similarity 167 member A
  family with sequence similarity 47 member B
  forkhead box D4 like 3
  GADD45G interacting protein 1
  glucose-fructose oxidoreductase domain containing 1
  G-patch domain containing 2 like
  kelch like family member 12
  keratin associated protein 10-8
  keratin associated protein 12-3
  keratin associated protein 26-1
  keratin associated protein 9-2
  keratin associated protein 9-3
  leukocyte receptor cluster member 1
  mago homolog B, exon junction complex subunit
  methyltransferase like 17
  microtubule interacting and trafficking domain containing 1
  Myb related transcription factor, partner of profilin
  myosin XIX
  myosin, heavy polypeptide 10, non-muscle
  NME/NM23 family member 7
  oligodendrocyte transcription factor 3
  PR/SET domain 14
  proline rich 35
  sodium channel modifier 1
  spermatogenesis associated 18
  TBC1 domain family member 22B
  TBC1 domain family member 26
  transcription factor AP-2 delta
  transmembrane protein 43
  tripartite motif containing 41
  ubiquitin specific peptidase 54
  ZFP1 zinc finger protein
  zinc finger and BTB domain containing 26
  zinc finger and SCAN domain containing 25
  zinc finger protein 250
  zinc finger protein 286A
  zinc finger protein 329
  zinc finger protein 366
  zinc finger protein 414
  zinc finger protein 415
  zinc finger protein 439
  zinc finger protein 440
  zinc finger protein 524
  zinc finger protein 552
  zinc finger protein 559
  zinc finger protein 564
  zinc finger protein 575
  zinc finger protein 581
  zinc finger protein 587
  zinc finger protein 613
  zinc finger protein 670
  zinc finger protein 775
  zinc finger protein 837

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.