MPI, mannose phosphate isomerase

MPI, mannose phosphate isomerase

• Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

• Gene Synonyms (CDG1B, PMI, PMI1, mannose-6-phosphate isomerase, phosphohexomutase, phosphomannose isomerase 1,)
• NCBI Gene ID: 4351
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NHZ6
  UNIPROT ID#>>H3BPP3
  UNIPROT ID#>>B4DW50
  UNIPROT ID#>>F5GX71
  UNIPROT ID#>>H3BPB8
  UNIPROT ID#>>P34949
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mannose phosphate isomerase interacts with:

• calpain 9
  DAZ associated protein 1
  GDP-mannose pyrophosphorylase B
  N-acetylneuraminate synthase
  NECAP endocytosis associated 1
  NECAP endocytosis associated 2
  NEDD8 ubiquitin like modifier
  phosphatidylinositol transfer protein beta
  pleckstrin homology domain containing A4
  poly(rC) binding protein 1
  S100 calcium binding protein A14
  serpin family B member 4
  sorcin
  superoxide dismutase 1
  TIA1 cytotoxic granule associated RNA binding protein
  transglutaminase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.