PAM16, presequence translocase associated motor 16

PAM16, presequence translocase associated motor 16

• This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

• Gene Synonyms (mitochondrial import inner membrane translocase subunit TIM16, magmas-like protein, mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction, mitochondria-associated granulocyte macrophage CSF-signaling molecule, presequence translocase associated motor 16 homolog, CGI-136, MAGMAS, SMDMDM, TIM16, TIMM16,)
• NCBI Gene ID: 51025
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y3D7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

presequence translocase associated motor 16 interacts with:

• ANTXR cell adhesion molecule 1
  ATP synthase membrane subunit DAPIT
  biogenesis of lysosomal organelles complex 1 subunit 2
  centrosomal protein 70
  chromosome 15 open reading frame 48
  coenzyme Q9
  coiled-coil domain containing 58
  DnaJ heat shock protein family (Hsp40) member C19
  ERGIC and golgi 3
  matrix AAA peptidase interacting protein 1
  mitochondrial amidoxime reducing component 1
  Morf4 family associated protein 1
  presequence translocase associated motor 16
  protein tyrosine phosphatase mitochondrial 1
  protocadherin alpha 12
  saccharopine dehydrogenase (putative)
  solute carrier family 25 member 29
  sperm acrosome associated 1
  testis expressed 29
  transcription factor B2, mitochondrial

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.