RLIM, ring finger protein, LIM domain interacting

RLIM, ring finger protein, LIM domain interacting

• The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]

• Gene Synonyms (E3 ubiquitin-protein ligase RLIM, E3 ubiquitin-protein ligase RNF12, LIM domain-interacting RING finger protein, R-LIM, RING finger LIM domain-binding protein, RING-type E3 ubiquitin transferase RLIM, renal carcinoma antigen NY-REN-43, ring finger protein 12, ring zinc finger LIM domain binding protein, ring zinc finger protein NY-REN-43antigen, MRX61, NY-REN-43, RNF12, TOKAS,)
• NCBI Gene ID: 51132
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NVW2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ring finger protein, LIM domain interacting interacts with:

• ligand of numb-protein X 2
  ring finger protein, LIM domain interacting
  RNA exonuclease 1 homolog
  SMAD specific E3 ubiquitin protein ligase 2
  toll interacting protein
  ubiquitin conjugating enzyme E2 D4 (putative)
  unk zinc finger
  UPF3B regulator of nonsense mediated mRNA decay

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.