UBAP1, ubiquitin associated protein 1

UBAP1, ubiquitin associated protein 1

• This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

• Gene Synonyms (ubiquitin-associated protein 1, nasopharyngeal carcinoma-associated gene 20 protein, NAG20, SPG80, UAP, UBAP, UBAP-1,)
• NCBI Gene ID: 51271
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZ09
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin associated protein 1 interacts with:

• armadillo like helical domain containing 3
  cell division cycle 37 like 1
  RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
  TNFAIP3 interacting protein 2
  ubiquitin associated protein 1
  vacuolar protein sorting 28
  VPS37A subunit of ESCRT-I
  VPS37B subunit of ESCRT-I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.