POMP, proteasome maturation protein

POMP, proteasome maturation protein

• The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]

• Gene Synonyms (proteasome maturation protein, 2510048O06Rik, hUMP1, proteassemblin, protein UMP1 homolog, voltage-gated K channel beta subunit 4.1, voltage-gated potassium channel beta subunit 4.1, C13orf12, HSPC014, PNAS-110, PRAAS2, UMP1,)
• NCBI Gene ID: 51371
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y244
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

proteasome maturation protein interacts with:

• centrosomal protein 120
  chromosome 16 open reading frame 70
  egl-9 family hypoxia inducible factor 3
  forkhead box R2
  proteasome assembly chaperone 2
  proteasome maturation protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.