RABGGTB, Rab geranylgeranyltransferase subunit beta

RABGGTB, Rab geranylgeranyltransferase subunit beta

• This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]

• Gene Synonyms (geranylgeranyl transferase type-2 subunit beta, GGTase-II-beta, Rab geranylgeranyltransferase beta subunit, rab GG transferase beta, rab GGTase beta, type II protein geranyl-geranyltransferase subunit beta, GGTB,)
• NCBI Gene ID: 5876
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P53611
  UNIPROT ID#>>A8KAJ2
  UNIPROT ID#>>Q6IB63
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rab geranylgeranyltransferase subunit beta interacts with:

• AAR2 splicing factor
  abraxas 1, BRCA1 A complex subunit
  acyl-CoA thioesterase 9
  A-kinase anchoring protein 11
  ATPase family AAA domain containing 5
  beta-1,4-galactosyltransferase 7
  BORA aurora kinase A activator
  calcium binding and coiled-coil domain 1
  family with sequence similarity 219 member A
  F-box and leucine rich repeat protein 2
  F-box and leucine rich repeat protein 20
  forkhead box K1
  G protein subunit beta 1 like
  GIT ArfGAP 1
  GIT ArfGAP 2
  hook microtubule tethering protein 1
  integrin alpha FG-GAP repeat containing 1
  limb development membrane protein 1 like
  MAGE family member D4B
  minichromosome maintenance complex binding protein
  nuclear receptor coactivator 1
  phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
  phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
  piggyBac transposable element derived 5
  proline rich coiled-coil 2C
  protein phosphatase 1 regulatory subunit 16A
  protein prenyltransferase alpha subunit repeat containing 1
  protein serine kinase H2
  protein tyrosine phosphatase 4A1
  protein tyrosine phosphatase 4A2
  Rab geranylgeranyltransferase subunit beta
  RAB11A, member RAS oncogene family
  RAB17, member RAS oncogene family
  RAB31, member RAS oncogene family
  RAB37, member RAS oncogene family
  RAB40B, member RAS oncogene family
  RAB40C, member RAS oncogene family
  RAB6B, member RAS oncogene family
  RAB7A, member RAS oncogene family
  RAB7B, member RAS oncogene family
  RAB9A, member RAS oncogene family
  RAB9B, member RAS oncogene family
  Rac/Cdc42 guanine nucleotide exchange factor 6
  RAP2A, member of RAS oncogene family
  RAP2C, member of RAS oncogene family
  RAS related 2
  Rho related BTB domain containing 3
  ribosomal protein S19
  ring finger protein 4
  SHANK associated RH domain interactor
  TAFA chemokine like family member 1
  transmembrane protein 25
  tripartite motif containing 33
  tRNA methyltransferase 2 homolog B
  WD repeat domain 4
  X-ray repair cross complementing 3
  YKT6 v-SNARE homolog
  zinc finger CCCH-type containing, antiviral 1 like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.