SLC9A1, solute carrier family 9 member A1

SLC9A1, solute carrier family 9 member A1

• This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth. [provided by RefSeq, Sep 2011]

• Gene Synonyms (sodium/hydrogen exchanger 1, Na(+)/H(+) exchanger 1, Na-Li countertransporter, protein phosphatase 1, regulatory subunit 143, solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive), solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive), solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1, APNH, LIKNS, NHE-1, NHE1, PPP1R143,)
• NCBI Gene ID: 6548
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P19634
  UNIPROT ID#>>B2RAH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 9 member A1 interacts with:

• adaptor related protein complex 4 subunit sigma 1
  amine oxidase copper containing 3
  calcineurin like EF-hand protein 1
  calcineurin like EF-hand protein 2
  coiled-coil domain containing 107
  family with sequence similarity 189 member A2
  fibronectin type III domain containing 5
  golgi-specific brefeldin A-resistance factor 1
  inositol-pentakisphosphate 2-kinase
  LY6/PLAUR domain containing 3
  MAD2 mitotic arrest deficient-like 1
  mitogen-activated protein kinase kinase kinase 14
  mitogen-activated protein kinase kinase kinase kinase 4
  OTU deubiquitinase with linear linkage specificity like
  polypeptide N-acetylgalactosaminyltransferase 6
  polypeptide N-acetylgalactosaminyltransferase 7
  RAB5C, member RAS oncogene family
  ribosomal protein S6 kinase A6
  semaphorin 7A (John Milton Hagen blood group)
  solute carrier family 20 member 1
  solute carrier organic anion transporter family member 6A1
  TATA-box binding protein associated factor 15
  tectonic family member 2
  tectonic family member 3
  tescalcin
  transmembrane protein 17
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  WNK lysine deficient protein kinase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.