STXBP1, syntaxin binding protein 1

STXBP1, syntaxin binding protein 1

• This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

• Gene Synonyms (syntaxin-binding protein 1, neuronal SEC1, protein unc-18 homolog 1, protein unc-18 homolog A, MUNC18-1, N-Sec1, NSEC1, P67, RBSEC1, UNC18, unc-18A, unc18-1,)
• NCBI Gene ID: 6812
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q68CM6
  UNIPROT ID#>>P61764
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

syntaxin binding protein 1 interacts with:

• actin related protein 2
  actin related protein 2/3 complex subunit 3
  actin related protein 3
  aminopeptidase puromycin sensitive
  armadillo repeat containing 1
  bolA family member 3
  cell division cycle associated 8
  centromere protein P
  chromosome 19 open reading frame 57
  cyclin dependent kinase 5 regulatory subunit 1
  cytidine/uridine monophosphate kinase 1
  DNA polymerase gamma 2, accessory subunit
  DnaJ heat shock protein family (Hsp40) member C11
  double C2 domain alpha
  double C2 domain beta
  dynein axonemal assembly factor 2
  EH domain containing 1
  fermitin family member 3
  G protein-coupled receptor class C group 5 member B
  GrpE like 1, mitochondrial
  HCLS1 associated protein X-1
  hepatocyte growth factor-regulated tyrosine kinase substrate
  huntingtin
  IQ motif containing B1
  metadherin
  nuclear FMR1 interacting protein 1
  nucleoporin 50
  phosphatase, orphan 1
  phosphatidylinositol binding clathrin assembly protein
  polo like kinase 2
  potassium channel tetramerization domain containing 10
  potassium channel tetramerization domain containing 3
  Rho GTPase activating protein 17
  ribosomal RNA processing 7 homolog A
  sequestosome 1
  SH3 domain binding glutamate rich protein like 3
  spindle and centriole associated protein 1
  squamous cell carcinoma antigen recognized by T cells 3
  succinate-CoA ligase ADP-forming subunit beta
  succinate-CoA ligase GDP/ADP-forming subunit alpha
  succinate-CoA ligase GDP-forming subunit beta
  synaptotagmin like 4
  syntaxin 11
  syntaxin 19
  syntaxin 1B
  transmembrane 4 L six family member 18
  tripartite motif containing 28
  tripartite motif containing 38
  tubulin alpha 4a
  tubulin beta 2A class IIa
  tumor suppressor candidate 3
  ubiquitin conjugating enzyme E2 N
  ubiquitin C-terminal hydrolase L1
  USO1 vesicle transport factor
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.