TAT, tyrosine aminotransferase

TAT, tyrosine aminotransferase

• This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008]

• Gene Synonyms (tyrosine aminotransferase, L-tyrosine:2-oxoglutarate aminotransferase, testis tissue sperm-binding protein Li 34a, tyrosine aminotransferase, cytosolic,)
• NCBI Gene ID: 6898
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VKB7
  UNIPROT ID#>>P17735
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tyrosine aminotransferase interacts with:

• alanyl-tRNA synthetase domain containing 1
  tyrosine aminotransferase
  ubiquitin protein ligase E3A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.