TCF12, transcription factor 12

TCF12, transcription factor 12

• The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription factor 12, DNA-binding protein HTF4, E-box-binding protein, class B basic helix-loop-helix protein 20, helix-loop-helix transcription factor 4, transcription factor HTF-4, CRS3, HEB, HTF4, HsT17266, TCF-12, bHLHb20, p64,)
• NCBI Gene ID: 6938
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R5T1
  UNIPROT ID#>>A0A024R5Z0
  UNIPROT ID#>>Q99081
  UNIPROT ID#>>F5GY10
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription factor 12 interacts with:

• achaete-scute family bHLH transcription factor 3
  achaete-scute family bHLH transcription factor 4
  ADP ribosylation factor like GTPase 16
  armadillo repeat containing 8
  Bcl2 modifying factor
  bMERB domain containing 1
  CGRP receptor component
  chromosome 1 open reading frame 109
  cilia and flagella associated protein 206
  DiGeorge syndrome critical region gene 6
  egl-9 family hypoxia inducible factor 3
  erythroid differentiation regulatory factor 1
  exocyst complex component 8
  exportin 1
  Fer3 like bHLH transcription factor
  FERM domain containing 6
  folliculogenesis specific bHLH transcription factor
  forkhead box H1
  golgi to ER traffic protein 4
  heart and neural crest derivatives expressed 1
  heart and neural crest derivatives expressed 2
  HEXIM P-TEFb complex subunit 2
  HOP homeobox
  hypoxia inducible factor 1 subunit alpha inhibitor
  inhibitor of DNA binding 2
  interferon regulatory factor 2 binding protein 2
  ligand of numb-protein X 1
  LysM domain containing 1
  mesoderm posterior bHLH transcription factor 2
  mesogenin 1
  mitogen-activated protein kinase binding protein 1
  MORN repeat containing 4
  musculin
  myosin XVB
  N-acetylglucosamine kinase
  neurogenin 3
  N-glycanase 1
  NIMA related kinase 6
  nuclear RNA export factor 1
  oligodendrocyte transcription factor 3
  oxidative stress induced growth inhibitor 1
  pancreas associated transcription factor 1a
  potassium channel tetramerisation domain containing 5
  RNA binding motif protein 8A
  SAGA complex associated factor 29
  serine protease 23
  serine/threonine kinase 16
  shugoshin 2A
  SPG21 abhydrolase domain containing, maspardin
  SRY-box transcription factor 8
  striatin 3
  TBC1 domain family member 21
  transcription factor 12
  transcription factor 21
  transcription factor 23
  translin associated factor X
  tripartite motif containing 25
  tripartite motif containing 33
  tripartite motif containing 72
  tumor protein p53 binding protein 1
  twist family bHLH transcription factor 2
  VPS28 subunit of ESCRT-I
  WT1 associated protein
  zinc finger protein 688
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.