VEGFB, vascular endothelial growth factor B

VEGFB, vascular endothelial growth factor B

• This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]

• Gene Synonyms (vascular endothelial growth factor B, VEGF-related factor, VEGFL, VRF,)
• NCBI Gene ID: 7423
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49765
  UNIPROT ID#>>Q7LAP4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

vascular endothelial growth factor B interacts with:

• ADAM metallopeptidase domain 21
  arachidonate lipoxygenase 3
  kelch like family member 12
  leucine rich repeat and fibronectin type III domain containing 3
  neuropilin 1
  nudix hydrolase 16 like 1
  tripartite motif containing 68
  vascular endothelial growth factor B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.