ZNF408, zinc finger protein 408

ZNF408, zinc finger protein 408

• The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016]

• Gene Synonyms (zinc finger protein 408, PR domain zinc finger protein 17, EVR6, RP72,)
• NCBI Gene ID: 79797
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DXY4
  UNIPROT ID#>>Q9H9D4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein 408 interacts with:

• AE binding protein 2
  APC membrane recruitment protein 1
  centrosomal protein 70
  chromosome alignment maintaining phosphoprotein 1
  cysteine rich tail 1
  fibronectin type III and SPRY domain containing 2
  Fraser extracellular matrix complex subunit 1
  keratin 40
  keratin associated protein 10-7
  keratin associated protein 10-8
  keratin associated protein 1-1
  keratin associated protein 12-2
  keratin associated protein 12-3
  keratin associated protein 4-12
  laminin subunit alpha 1
  leucine zipper tumor suppressor 2
  mirror-image polydactyly 1
  mitochondrial ribosome recycling factor
  NBPF member 19
  notch 2 N-terminal like A
  RALY RNA binding protein like
  RNA binding motif protein Y-linked family 1 member F
  RNA binding motif protein Y-linked family 1 member J
  SHC binding and spindle associated 1
  sprouty related EVH1 domain containing 1
  SSX family member 2 interacting protein
  tripartite motif containing 41
  WD repeat and coiled coil containing
  zinc finger and BTB domain containing 8A
  zinc finger and BTB domain containing 8B
  zinc finger and BTB domain containing 9
  zinc finger protein 408
  zinc finger protein 526
  zinc finger protein 764
  zinc finger protein 792
  zinc finger protein 837

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.