TRIM8, tripartite motif containing 8

TRIM8, tripartite motif containing 8

• This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016]

• Gene Synonyms (E3 ubiquitin-protein ligase TRIM8, RING-type E3 ubiquitin transferase TRIM8, glioblastoma-expressed RING finger protein, probable E3 ubiquitin-protein ligase TRIM8, ring finger protein 27, tripartite motif protein TRIM8, GERP, RNF27,)
• NCBI Gene ID: 81603
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BZR9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tripartite motif containing 8 interacts with:

• cation channel sperm associated 1
  ligand of numb-protein X 1
  LON peptidase N-terminal domain and ring finger 1
  maturin, neural progenitor differentiation regulator homolog
  nudix hydrolase 10
  polycomb group ring finger 5
  ring finger protein 168
  toll like receptor adaptor molecule 1
  tripartite motif containing 15
  tripartite motif containing 43
  tripartite motif containing 47
  tripartite motif containing 8
  tripartite motif containing 9
  ubiquitin like with PHD and ring finger domains 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.