MAD1L1, mitotic arrest deficient 1 like 1

MAD1L1, mitotic arrest deficient 1 like 1

• MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (mitotic spindle assembly checkpoint protein MAD1, MAD1 mitotic arrest deficient like 1, MAD1-like protein 1, mitotic arrest deficient 1-like protein 1, mitotic checkpoint MAD1 protein homolog, mitotic-arrest deficient 1, yeast, homolog-like 1, tax-binding protein 181, tumor protein p53 inducible protein 9, MAD1, PIG9, TP53I9, TXBP181,)
• NCBI Gene ID: 8379
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6D9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitotic arrest deficient 1 like 1 interacts with:

• angiomotin like 2
  ankyrin repeat and SOCS box containing 7
  autophagy related 5
  BAG cochaperone 5
  calpain 7
  caveolae associated protein 1
  cell division cycle 37, HSP90 cochaperone
  chromosome 6 open reading frame 141
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 57
  CWF19 like cell cycle control factor 2
  cyclin-dependent kinase 1
  family with sequence similarity 131 member C
  family with sequence similarity 90 member A1
  forkhead box J2
  galectin like
  G-patch domain and KOW motifs
  HAUS augmin like complex subunit 1
  IKAROS family zinc finger 3
  kinesin family member 9
  leukocyte receptor cluster member 1
  ligand of numb-protein X 1
  LIM domain only 3
  MAD2 mitotic arrest deficient-like 1
  MAD2L1 binding protein
  MAD2L1 binding protein
  methyltransferase like 21C
  mitotic arrest deficient 1 like 1
  NDC80 kinetochore complex component
  nebulette
  ninein like
  N-terminal glutamine amidase 1
  nuclear distribution C, dynein complex regulator
  potassium voltage-gated channel subfamily A regulatory beta subunit 3
  progesterone immunomodulatory binding factor 1
  protein phosphatase 1 regulatory subunit 18
  ring finger protein 8
  scavenger receptor class A member 3
  serine/threonine kinase 24
  SIN3 transcription regulator family member A
  SIN3 transcription regulator family member B
  SNW domain containing 1
  spermatogenesis associated 18
  spermatogenesis associated 2
  SUMO specific peptidase 3
  synaptotagmin 17
  synaptotagmin 6
  teashirt zinc finger homeobox 3
  testis expressed 11
  testis expressed 33
  testis specific 10
  thyroid hormone receptor interactor 13
  tripartite motif containing 29
  TRPM8 channel associated factor 1
  tubulin gamma complex associated protein 4
  ubiquitin specific peptidase 15
  VPS28 subunit of ESCRT-I
  YJU2 splicing factor homolog
  zinc binding alcohol dehydrogenase domain containing 2
  zinc finger and SCAN domain containing 32
  zinc finger ZZ-type and EF-hand domain containing 1
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.