GPAA1, glycosylphosphatidylinositol anchor attachment 1

GPAA1, glycosylphosphatidylinositol anchor attachment 1

• Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]

• Gene Synonyms (glycosylphosphatidylinositol anchor attachment 1 protein, GAA1 protein homolog, GPAA1P anchor attachment protein 1 homolog, GPI anchor attachment protein 1, GPI transamidase subunit, anchor attachment protein 1 (Gaa1p, yeast) homolog, glycophosphatidylinositol anchor attachment 1, glycosylphosphatidylinositol anchor attachment protein 1 homolog, GAA1, GPIBD15, hGAA1,)
• NCBI Gene ID: 8733
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43292
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycosylphosphatidylinositol anchor attachment 1 interacts with:

• 5-hydroxytryptamine receptor 3C
  ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
  LY6/PLAUR domain containing 3
  monooxygenase DBH like 1
  mucolipin 3
  phosphatidylinositol glycan anchor biosynthesis class K
  phosphatidylinositol glycan anchor biosynthesis class S
  phosphatidylinositol glycan anchor biosynthesis class T
  phosphatidylinositol glycan anchor biosynthesis class U
  pleckstrin homology domain containing A4
  potassium two pore domain channel subfamily K member 16
  proline rich 13
  protein tyrosine phosphatase, non-receptor type 13
  Rho-associated coiled-coil containing protein kinase 1
  serine protease 50
  tectonic family member 3
  trehalase
  vanin 2
  Yip1 domain family member 3
  zinc activated ion channel

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.