DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B

DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B

• This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Gene Synonyms (dual specificity tyrosine-phosphorylation-regulated kinase 1B, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B, minibrain-related kinase, mirk protein kinase, AOMS3, MIRK,)
• NCBI Gene ID: 9149
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0J6
  UNIPROT ID#>>A0A024R0M8
  UNIPROT ID#>>Q9Y463
  UNIPROT ID#>>A0A024R0I0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dual specificity tyrosine phosphorylation regulated kinase 1B interacts with:

• A-kinase anchoring protein 11
  ATPase family AAA domain containing 3B
  chromosome 10 open reading frame 71
  DDB1 and CUL4 associated factor 4
  DDB1 and CUL4 associated factor 7
  dual specificity tyrosine phosphorylation regulated kinase 1B
  E1A binding protein p400
  egl-9 family hypoxia inducible factor 2
  ENAH actin regulator
  family with sequence similarity 117 member A
  family with sequence similarity 117 member B
  family with sequence similarity 53 member C
  forkhead box K1
  glucocorticoid induced 1
  histone deacetylase 5
  homeodomain interacting protein kinase 2
  interactor of little elongation complex ELL subunit 1
  interactor of little elongation complex ELL subunit 2
  KIAA0232
  leucine zipper tumor suppressor 2
  leucine zipper tumor suppressor family member 3
  lysine acetyltransferase 8
  mediator complex subunit 23
  mitotic spindle positioning
  MSL complex subunit 3
  prostaglandin E synthase 3
  protein phosphatase 1 regulatory subunit 3F
  RAN binding protein 9
  ring finger protein 169
  signal induced proliferation associated 1 like 1
  signal induced proliferation associated 1 like 2
  signal induced proliferation associated 1 like 3
  STIP1 homology and U-box containing protein 1
  trans-2,3-enoyl-CoA reductase
  transcription elongation factor A like 1
  trophinin associated protein
  WD repeat domain 6
  zinc finger protein 516

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.