USP16, ubiquitin specific peptidase 16

USP16, ubiquitin specific peptidase 16

• This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (UBP-M, UBPM, ubiquitin carboxyl-terminal hydrolase 16, deubiquitinating enzyme 16, ubiquitin specific protease 16, ubiquitin thioesterase 16, ubiquitin thiolesterase 16, ubiquitin-processing protease UBP-M, ubiquitin-specific processing protease 16,)
• NCBI Gene ID: 10600
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5T5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin specific peptidase 16 interacts with:

• apolipoprotein M
  F-box protein 11
  H4 histone 16
  insulin like growth factor 2 mRNA binding protein 3
  neuralized E3 ubiquitin protein ligase 4
  pleckstrin homology domain containing A4
  PTOV1 extended AT-hook containing adaptor protein
  SRP receptor subunit beta
  SUZ12 polycomb repressive complex 2 subunit
  ubiquitin specific peptidase 16
  WD repeat domain 54

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.