AKAP10, A-kinase anchoring protein 10

AKAP10, A-kinase anchoring protein 10

• This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012]

• Gene Synonyms (A-kinase anchor protein 10, mitochondrial, A kinase (PRKA) anchor protein 10, A kinase anchor protein 10, dual specificity A kinase-anchoring protein 2, mitochondrial A kinase PPKA anchor protein 10, protein kinase A anchoring protein 10, AKAP-10, D-AKAP-2, D-AKAP2, PRKA10,)
• NCBI Gene ID: 11216
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43572
  UNIPROT ID#>>E7EMD6
  UNIPROT ID#>>A0A0S2Z4Z7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

A-kinase anchoring protein 10 interacts with:

• component of oligomeric golgi complex 3
  dynactin subunit 4
  IKAROS family zinc finger 3
  pleckstrin homology domain containing A4
  SAM and SH3 domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.