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TREX1, three prime repair exonuclease 1

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TREX1, three prime repair exonuclease 1

  • This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

  • Gene Synonyms (three-prime repair exonuclease 1, 3' repair exonuclease 1, 3'-5' exonuclease TREX1, DNase III, deoxyribonuclease III, AGS1, CRV, DRN3, HERNS,)
  • NCBI Gene ID: 11277
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q9NSU2
    UNIPROT ID#>>Q5TZT0
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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