DIMT1, DIMT1 rRNA methyltransferase and ribosome maturation factor

DIMT1, DIMT1 rRNA methyltransferase and ribosome maturation factor

• The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017]

• Gene Synonyms (probable dimethyladenosine transferase, 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, 18S rRNA dimethylase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase, dimethyladenosine transferase, probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, probable 18S rRNA dimethylase, probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase, DIM1, DIMT1L, HSA9761, HUSSY5,)
• NCBI Gene ID: 27292
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNQ2
  UNIPROT ID#>>A8K9K8
  UNIPROT ID#>>A0A0C4DGB1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DIMT1 rRNA methyltransferase and ribosome maturation factor interacts with:

• aurora kinase A interacting protein 1
  chromobox 8
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 55
  DnaJ heat shock protein family (Hsp40) member C21
  eukaryotic translation initiation factor 3 subunit K
  G protein-coupled receptor associated sorting protein 2
  glutamate rich WD repeat containing 1
  La ribonucleoprotein 7, transcriptional regulator
  mitochondrial poly(A) polymerase
  pleckstrin homology domain containing A4
  replication initiator 1
  ring finger and CCCH-type domains 1
  RIO kinase 1
  thiamine triphosphatase
  ubiquitin specific peptidase 42
  zinc finger and BTB domain containing 7A
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.