ZC3HC1, zinc finger C3HC-type containing 1

ZC3HC1, zinc finger C3HC-type containing 1

• This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]

• Gene Synonyms (nuclear-interacting partner of ALK, hematopoietic stem/progenitor cell protein 216, nuclear interacting partner of anaplastic lymphoma kinase (ALK), HSPC216, NIPA,)
• NCBI Gene ID: 51530
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86WB0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger C3HC-type containing 1 interacts with:

• aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  ATPase H+ transporting V1 subunit C2
  ethanolamine-phosphate phospho-lyase
  MINDY lysine 48 deubiquitinase 3
  nuclear RNA export factor 2B
  pleckstrin homology domain containing A4
  S1 RNA binding domain 1
  SAS-6 centriolar assembly protein
  TAFA chemokine like family member 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.