SF3B6, splicing factor 3b subunit 6

SF3B6, splicing factor 3b subunit 6

• This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. [provided by RefSeq, Jul 2008]

• Gene Synonyms (splicing factor 3B subunit 6, SF3b 14 kDa subunit, pre-mRNA branch site protein p14, spliceosome-associated protein, 14 kDa subunit, spliceosome-associated protein, 14-kDa, splicing factor 3B, 14 kDa subunit, splicing factor 3b, subunit 6, 14kDa, CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a,)
• NCBI Gene ID: 51639
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y3B4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

splicing factor 3b subunit 6 interacts with:

• argonaute RISC catalytic component 3
  autophagy related 16 like 1
  coiled-coil domain containing 97
  cullin associated and neddylation dissociated 1
  FtsJ RNA 2'-O-methyltransferase 3
  integrin alpha FG-GAP repeat containing 1
  intraflagellar transport 22
  minichromosome maintenance 9 homologous recombination repair factor
  PHD finger protein 5A
  pleckstrin homology domain containing A4
  protein phosphatase 4 regulatory subunit 2
  pyrin and HIN domain family member 1
  splicing factor 3a, subunit 1
  splicing factor 3b subunit 5
  splicing factor 3b subunit 6
  THO complex 6
  TNFAIP3 interacting protein 2
  tripartite motif containing 55
  WD repeat domain 18
  WW domain containing oxidoreductase
  zinc finger CCCH-type containing 18
  zinc finger protein 326

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