PBRM1, polybromo 1

PBRM1, polybromo 1

• This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]

• Gene Synonyms (BAF180, PB1, protein polybromo-1, BRG1-associated factor 180, polybromo-1D,)
• NCBI Gene ID: 55193
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86U86
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

polybromo 1 interacts with:

• AT-rich interaction domain 2
  chromodomain helicase DNA binding protein 7
  developmental pluripotency associated 4
  E1A binding protein p400
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  Nanog homeobox
  pleckstrin homology domain containing A4
  polybromo 1
  required for meiotic nuclear division 5 homolog A
  signal recognition particle 72
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  trichohyalin like 1
  ubiquitin like with PHD and ring finger domains 2
  WD repeat domain 76
  zinc finger protein 512B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.