DDX28, DEAD-box helicase 28

DDX28, DEAD-box helicase 28

• DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]

• Gene Synonyms (MDDX28, probable ATP-dependent RNA helicase DDX28, DEAD (Asp-Glu-Ala-Asp) box polypeptide 28, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 28, mitochondrial DEAD box protein 28, mitochondrial DEAD-box polypeptide 28,)
• NCBI Gene ID: 55794
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NUL7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DEAD-box helicase 28 interacts with:

• excision repair cross-complementing rodent repair deficiency complementation group 6 like
  mitochondrial assembly of ribosomal large subunit 1
  mitochondrial fission factor
  mitochondrial ribosomal protein L11
  mitochondrial ribosomal protein L17
  mitochondrial ribosomal protein L32
  mitochondrial ribosomal protein L52
  mitochondrial ribosomal protein L57
  mitochondrial ribosomal protein L9
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  pleckstrin homology domain containing A4
  ring finger and CCCH-type domains 1
  RIO kinase 1
  RNA pseudouridine synthase D4
  TNFAIP3 interacting protein 2
  transmembrane protein 43
  ubiquitin protein ligase E3 component n-recognin 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.