NSFL1C, NSFL1 cofactor

NSFL1C, NSFL1 cofactor

• N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011]

• Gene Synonyms (P47, UBX1, UBXD10, UBXN2C, dJ776F14.1, NSFL1 cofactor p47, NSFL1 (p97) cofactor (p47), SHP1 homolog, UBX domain-containing protein 2C, p97 cofactor p47,)
• NCBI Gene ID: 55968
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53FE8
  UNIPROT ID#>>Q9UNZ2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NSFL1 cofactor interacts with:

• acyl-CoA dehydrogenase family member 11
  agrin
  ASPSCR1 tether for SLC2A4, UBX domain containing
  family with sequence similarity 104 member A
  lactamase beta
  NUF2 component of NDC80 kinetochore complex
  poly(ADP-ribose) polymerase family member 6
  PTEN induced kinase 1
  SprT-like N-terminal domain
  TatD DNase domain containing 1
  tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
  ubiquitin like modifier activating enzyme 5
  ubiquitin protein ligase E3 component n-recognin 1
  UBX domain protein 10
  UBX domain protein 2A
  UBX domain protein 6
  valosin containing protein interacting protein 1
  zinc finger and BTB domain containing 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.