PDCD5, programmed cell death 5

PDCD5, programmed cell death 5

• This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]

• Gene Synonyms (programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TF1 cell apoptosis-related gene 19, TFAR19 novel apoptosis-related, TFAR19,)
• NCBI Gene ID: 9141
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14737
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

programmed cell death 5 interacts with:

• arrestin domain containing 5
  centrosomal protein 126
  chaperonin containing Tcp1, subunit 2 (beta)
  chaperonin containing Tcp1, subunit 3 (gamma)
  chaperonin containing Tcp1, subunit 4 (delta)
  chaperonin containing Tcp1, subunit 7 (eta)
  chaperonin containing Tcp1, subunit 8 (theta)
  EEF1A lysine methyltransferase 3
  F-box and WD repeat domain containing 8
  ligand dependent nuclear receptor interacting factor 1
  lysine acetyltransferase 5
  lysine demethylase 1A
  nudix hydrolase 3
  OTU deubiquitinase 5
  phosphoethanolamine/phosphocholine phosphatase 1
  protein interacting with PRKCA 1
  RAD18 E3 ubiquitin protein ligase
  transcription elongation factor A like 1
  tripartite motif containing 35
  UTP14A small subunit processome component
  YY1 associated factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.