NUDT3, nudix hydrolase 3

NUDT3, nudix hydrolase 3

• NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM, Feb 2011]

• Gene Synonyms (diphosphoinositol polyphosphate phosphohydrolase 1, diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1, nucleoside diphosphate-linked moiety X motif 3, nudix (nucleoside diphosphate linked moiety X)-type motif 3, nudix motif 3, DIPP, DIPP-1, DIPP1,)
• NCBI Gene ID: 11165
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95989
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nudix hydrolase 3 interacts with:

• ADP ribosylation factor like GTPase 6 interacting protein 1
  ankyrin repeat and SOCS box containing 13
  coiled-coil-helix-coiled-coil-helix domain containing 3
  integrin alpha FG-GAP repeat containing 1
  MAF1 homolog, negative regulator of RNA polymerase III
  mex-3 RNA binding family member B
  N(alpha)-acetyltransferase 15, NatA auxiliary subunit
  protein kinase D3
  RAB17, member RAS oncogene family
  ring finger protein 126
  tubulin gamma complex associated protein 4
  tubulin tyrosine ligase-like family, member 7
  ubiquitin protein ligase E3 component n-recognin 1
  WD repeat domain 74

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.