PTDSS1, phosphatidylserine synthase 1

PTDSS1, phosphatidylserine synthase 1

• The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]

• Gene Synonyms (phosphatidylserine synthase 1, PSS-1, ptdSer synthase 1, serine-exchange enzyme I, LMHD, PSS1, PSSA,)
• NCBI Gene ID: 9791
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48651
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylserine synthase 1 interacts with:

• ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  bromodomain containing 7
  cAMP responsive element binding protein 3
  clusterin associated protein 1
  dynactin 1
  hypoxia inducible factor 1 subunit alpha inhibitor
  kinectin 1
  polo like kinase 4
  survival motor neuron 1
  tectonic family member 2
  tectonic family member 3
  transmembrane p24 trafficking protein 2
  transmembrane protein 41B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.