B3GNT3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

B3GNT3, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

• This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]

• Gene Synonyms (B3GAL-T8, B3GN-T3, B3GNT-3, HP10328, TMEM3, beta3Gn-T3, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3, UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8, UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8, beta-1,3-GalTase 8, beta-1,3-Gn-T3, beta-1,3-N-acetylglucosaminyltransferase bGnT-3, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase, beta-3-Gx-T8, beta3GalT8, core 1 extending beta-1,3-N-acetylglucosaminyltransferase, core1-beta3GlcNAcT, putative type II membrane protein, transmembrane protein 3,)
• NCBI Gene ID: 10331
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y2A9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 interacts with:

• adhesion molecule with Ig like domain 1
  chondroitin sulfate N-acetylgalactosaminyltransferase 2
  chromosome 6 open reading frame 120
  dual serine/threonine and tyrosine protein kinase
  growth hormone inducible transmembrane protein
  leucine rich repeat and fibronectin type III domain containing 3
  membrane bound O-acyltransferase domain containing 7
  phosphatidylinositol glycan anchor biosynthesis class U
  polypeptide N-acetylgalactosaminyltransferase 12
  polypeptide N-acetylgalactosaminyltransferase 7
  progesterone receptor membrane component 1
  protein O-glucosyltransferase 2
  selenoprotein N
  solute carrier family 30 member 5
  solute carrier family 30 member 6
  solute carrier family 30 member 7
  tubulin beta 8 class VIII

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