TACC3, transforming acidic coiled-coil containing protein 3

TACC3, transforming acidic coiled-coil containing protein 3

• This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011]

• Gene Synonyms (ERIC-1, ERIC1, Tacc4, maskin, transforming acidic coiled-coil-containing protein 3,)
• NCBI Gene ID: 10460
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6A5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transforming acidic coiled-coil containing protein 3 interacts with:

• adenosylhomocysteinase like 1
  aristaless related homeobox
  ASPSCR1 tether for SLC2A4, UBX domain containing
  biorientation of chromosomes in cell division 1 like 1
  BLOC-1 related complex subunit 6
  brain expressed X-linked 2
  brain expressed X-linked 3
  C2 calcium dependent domain containing 6
  calcium and integrin binding family member 3
  CAP-Gly domain containing linker protein family member 4
  cell division cycle 20B
  chibby family member 2
  chromosome 2 open reading frame 69
  coiled-coil alpha-helical rod protein 1
  complexin 1
  coronin 6
  cytoskeleton associated protein 5
  DDB1 and CUL4 associated factor 15
  DEP domain containing 7
  ENAH actin regulator
  Enah/Vasp-like
  family with sequence similarity 111 member B
  fizzy and cell division cycle 20 related 1
  FRY like transcription coactivator
  HSPA (Hsp70) binding protein 1
  IQ motif containing D
  kelch like family member 38
  kizuna centrosomal protein
  methyltransferase like 14
  MIA SH3 domain ER export factor 3
  mitogen-activated protein kinase kinase kinase 21
  nucleoporin 54
  nucleotide binding oligomerization domain containing 2
  nudE neurodevelopment protein 1 like 1
  Opa interacting protein 5
  origin recognition complex subunit 3
  pantothenate kinase 2
  peptide deformylase, mitochondrial
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  pleckstrin homology domain containing O2
  proline rich 14 like
  protein arginine methyltransferase 9
  PTEN induced kinase 1
  RAB14, member RAS oncogene family
  ring finger protein 123
  ring finger protein 135
  ring finger protein 168
  ring finger protein 20
  Sec23 homolog A, COPII coat complex component
  SEC24 homolog A, COPII coat complex component
  SLAIN motif family member 2
  sorting nexin 20
  spermatogenesis associated 18
  sulfiredoxin 1
  TBC1 domain family member 22B
  transforming, acidic coiled-coil containing protein 3
  vir like m6A methyltransferase associated
  VPS37C subunit of ESCRT-I
  WD repeat domain 90
  zinc finger C3H1-type containing
  zinc ribbon domain containing 2
  ZW10 interactor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.