OGFR, opioid growth factor receptor

OGFR, opioid growth factor receptor

• The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]

• Gene Synonyms (opioid growth factor receptor, protein 7-60, zeta-type opioid receptor,)
• NCBI Gene ID: 11054
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZT2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

opioid growth factor receptor interacts with:

• AAR2 splicing factor
  cell division cycle 37, HSP90 cochaperone
  clusterin associated protein 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  shootin 1
  TERF2 interacting protein
  TGFB induced factor homeobox 2 like Y-linked
  tRNA methyltransferase 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.