SOX30, SRY-box transcription factor 30

SOX30, SRY-box transcription factor 30

• This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Apr 2015]

• Gene Synonyms (transcription factor SOX-30, SRY (sex determining region Y)-box 30, SRY-box 30, Sox30 protein type II,)
• NCBI Gene ID: 11063
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94993
  UNIPROT ID#>>B4DXW7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SRY-box transcription factor 30 interacts with:

• BMP and activin membrane bound inhibitor
  cilia and flagella associated protein 206
  DDB1 and CUL4 associated factor 4
  DEAD-box helicase 56
  F-box protein 38
  nudix hydrolase 3
  PAX interacting protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.