DDX56, DEAD-box helicase 56

DDX56, DEAD-box helicase 56

• This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

• Gene Synonyms (probable ATP-dependent RNA helicase DDX56, 61-kd nucleolar helicase, ATP-dependent 61 kDa nucleolar RNA helicase, DEAD (Asp-Glu-Ala-Asp) box helicase 56, DEAD (Asp-Glu-Ala-Asp) box polypeptide 56, DEAD box protein 21, DEAD box protein 56, DEAD-box RNA helicase, nucleolar helicase of 61 kDa, putative nucleolar RNA helicase, DDX21, DDX26, NOH61,)
• NCBI Gene ID: 54606
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NY93
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DEAD-box helicase 56 interacts with:

• aurora kinase A interacting protein 1
  autophagy related 16 like 1
  biogenesis of ribosomes BRX1
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 24
  DEAD-box helicase 55
  DEAD-box helicase 56
  DEAH-box helicase 37
  DExH-box helicase 57
  FtsJ RNA 2'-O-methyltransferase 3
  glutamate rich WD repeat containing 1
  G-patch domain containing 4
  MAGE family member B10
  mitochondrial ribosomal protein L43
  mitochondrial ribosomal protein S14
  mitochondrial ribosomal protein S24
  mitochondrial ribosomal protein S25
  mitochondrial ribosomal protein S34
  mitochondrial ribosomal protein S5
  mitochondrial ribosomal protein S9
  peter pan homolog
  pleckstrin homology domain containing A4
  ribosome production factor 2 homolog
  ring finger and CCCH-type domains 1
  RIO kinase 1
  WD repeat domain 36
  zinc finger protein 408

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.