PPP1R13B, protein phosphatase 1 regulatory subunit 13B

PPP1R13B, protein phosphatase 1 regulatory subunit 13B

• This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ASPP1, p53BP2-like, p85, apoptosis-stimulating of p53 protein 1, apoptosis-stimulating protein of p53, 1, protein phosphatase 1, regulatory (inhibitor) subunit 13B,)
• NCBI Gene ID: 23368
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96KQ4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 1 regulatory subunit 13B interacts with:

• acyl-CoA synthetase family member 3
  autophagy related 16 like 1
  calpain 7
  carboxypeptidase vitellogenic like
  centrosomal protein 128
  centrosomal protein 63
  chibby family member 2
  chromosome 2 open reading frame 42
  cingulin
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 102B
  coiled-coil domain containing 184
  coiled-coil domain containing 85C
  deuterosome assembly protein 1
  DiGeorge syndrome critical region gene 6 like
  DIRAS family GTPase 1
  family with sequence similarity 184 member A
  family with sequence similarity 90 member A1
  GINS complex subunit 4
  growth arrest specific 2 like 2
  keratin 20
  kinesin family member 9
  lamin B2
  large tumor suppressor kinase 2
  ligand of numb-protein X 1
  LIM domain only 3
  mirror-image polydactyly 1
  MIS18 kinetochore protein A
  NHS like 2
  ninein
  pleckstrin homology domain containing A5
  proline rich 35
  protein phosphatase 1 regulatory subunit 18
  Ras association domain family member 10
  RAS protein activator like 3
  Rho GTPase activating protein 45
  SSX family member 2 interacting protein
  suppressor of glucose, autophagy associated 1
  taxilin alpha
  tektin 4
  testis expressed 12
  testis expressed 9
  testis specific 10
  vir like m6A methyltransferase associated
  zinc finger CCCH-type and G-patch domain containing
  zinc finger ZZ-type containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.